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Much of it is broken down in the gut before it can reach your bloodstream
-Cell is vulnerable to reactive oxygen species (ROS) 7,8
At high doses, RSV can inhibit cytochrome P450 (CYP3A4) enzymes (54), altering the metabolism of co-administered drugs and potentially leading to adverse effects
DOI: 10.1016/j.jneuroim.2016.08.012 21
329 Paradoxically, a study showed that AML cell death after APR-246 treatment is inhibited by iron chelators, inhibitors of lipid peroxidation, and lipophilic antioxidants and is characterized by the accumulation of lipid peroxidation, thus meeting the definition of ferroptosis
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