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Evidence confirming the role of PYY 3-36 in inducing anorexia has been obtained in mice by direct injection of the peptide into the ARC
There is currently no conclusive clinical research evidence to support this
Semaglutide , available as once-weekly injection (Ozempic, Wegovy) or daily oral tablet (Rybelsus), has demonstrated robust effects on weight loss and cardiovascular outcomes in the SUSTAIN and STEP trial programmes
If weight loss stalls despite adherence, see Increase Weight Loss on Wegovy for incremental strategies such as protein targets and step goals
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