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[5] [6] The guideline emphasises a stepwise approach to treatment intensification, typically progressing from metformin monotherapy to dual therapy (often with an SGLT2 inhibitor, DPP-4 inhibitor, pioglitazone, or sulphonylurea), and then to triple therapy or insulin-based regimens

And the critical difference between skin sensitivity that will resolve on its own and symptoms that demand medical attention

Glucagon-like peptide-1 (GLP-1) receptor agonists are a class of medications primarily prescribed for the management of type 2 diabetes mellitus and, more recently, for weight management in adults with obesity